| Business Name | Type of Business | Physical Address | Phone |
| Advance Auto Parts | Automotive | 11535 Hwy 57 | 826-3900 |
| Agape Termite Services | Pest Control | 4800 Poticaw Bayou Rd | 826-3123 |
| Alicia Jackson, Coldwell Banker United Realtors * | Real Estate | 13004 Little Bluff Dr | 826-5887 |
| AllWill Management LLC | Specialties | 13460 Ridgeland Rd | 826-3434 |
| Blossman Gas & Appliance | Specialties | 12513 Hwy 57 | 826-5997 |
| Bluff Creek Campground + | Recreation | 4301 Poticaw Bayou Rd | 826-3958 |
| Bluff Creek Equipment Rental | Retail / Rental Stores | 11988 Hwy 57 | 826-1414 |
| BMT Electric | Construction, Services & Hardware | 13300 Ware Lake Rd | 826-1133 |
| BNB Video | Dining | 12609 Hwy 57 | 826-0022 |
| Burnham's Drugs | Health & Beauty | 12500 Hwy 57 | 826-4747 |
| Byers American TaeKwondo Academy | Recreation | 5613 CL Dees Dr | 826-9908 |
| Century Bank | Financial | 11612 Hwy 57 | 826-9906 |
| Coast Water Well Service, Inc | Construction, Services & Hardware | 5525 CL Dees Dr | 826-9275 |
| Coles Service Center * + | Automotive | 4800 Poticaw Bayou Rd | 826-5121 |
| Creations & More Gourmet Coffee & Gifts | Dining | 12219 Hwy 57 | 826-3223 |
| Dahl's NAPA Auto Parts * | Automotive | 12216 Hwy 57 | 826-5762 |
| Digital Security Systems LLC | Specialties | 15412 Old River Rd | 218-9988 |
| Discount Pawn * | Retail / Rental Stores | 12622 Hwy 57 | 826-4556 |
| Dr. Edward J Banas, DDS * + | Medical | 11938 Hwy 57 | 826-3811 |
| DSLByAir Internet Services | Specialties | 21608 Old River Rd | 238-2563 |
| Eagle 2 Graphics | Specialties | Hwy 57 | 826-9457 |
| First Federal Savings & Loan * | Financial | 10900 Hwy 57 | 826-9130 |
| First Pentecoastal Church of Vancleave | Churches | 10816 Hwy 57 | 826-2910 |
| Florist At Heart - Sues | Retail / Rental Stores | 4801 B Moungers Creek | 826-4421 |
| GCIS * | Specialties | 13520 Havens Rd | 826-5832 |
| Hancock Bank * | Financial | 11004 Hwy 57 | 934-4348 |
| Helen Cramer, Realtor | Real Estate | 15501 Omas Rd | 990-0133 |
| Holy Spirit Catholic Church | Churches | 6705 Jim Ramsey Rd. | 826-4008 |
| HP Davis Grocery * | Retail / Rental Stores | 12601 Hwy 57 | 826-5275 |
| Integrity Insurance Providers * | Insurance | 11988 Hwy 57 Ste A | 826-3530 |
| Jesse's Concrete | Construction, Services & Hardware | 13300 Ridgeland Rd | 826-2721 |
| Joe West Realty | Real Estate | 4101 Gautier Vancleave Rd #5 | 497-3797 |
| John M Ford, Atty | Attorney | PO Box 1655 | 826-5367 |
| Joleen's Starz of S. Performing Arts Studio | Recreation | | 826-3722 |
| Kelli's Step School of Dance | Recreation | 11628 Hwy 57 Ste D | 388-1616 |
| Kid Korral | Specialties | 14104 Hwy 57 | 826-2040 |
| Lane Constuction * | Construction, Services & Hardware | 3909 Hwy 57 | 872-2414 |
| Metro Concrete * | Construction, Services & Hardware | 3935 Hwy 57 | 872-2028 |
| Meyer's Auto Salvage | Automotive | 9113 Hwy 57 | 826-5792 |
| Mohler's Donut Hut * | Dining | 11988 Hwy 57 Ste C | 826-9138 |
| Morrison Animal Clinic | Veternarians | 5001 Jim Ramsay Rd | 826-4833 |
| Navigator Credit Union - Vancleave Branch * | Financial | 11638 Hwy 57 | 474-3452 |
| Noblitt & Associates + | Financial | 12004 Hwy 57 | 826-3600 |
| O'Bryant-O'Keefe Funeral Home | Specialties | Jim Ramsey Rd | 826-4311 |
| Professional Auto Collision | Automotive | 12716 Hwy 57 | 826-2387 |
| Ralph King Jr. Builder | Construction, Services & Hardware | 3301 Bluewood Dr. | 826-4429 |
| RSP Graphics * | Specialties | 4628 Breland Rd | 826-1277 |
| Sav-Rex Drugs - Vancleave Store * | Health & Beauty | 11936 Hwy 57 | 826-4403 |
| Sound Escapes | Specialties | 4400 Chico Rd | 217-2627 |
| Southern Lift, Inc * | Specialties | 11008 Hwy 57 | 826-5257 |
| Stormy Hurricane Shutters LLC * | Construction, Services & Hardware | 4800 Poticaw Bayou Rd | 238-3298 |
| Subway | Dining | 11628 Hwy 57 | 826-0051 |
| Sunset Photography | Specialties | 7530 Hy 57 Ste C | 872-9754 |
| Terry Miller, Jackson County Chancery Clerk | Government | 310 Magnolia St | 769-3499 |
| The Sod Outlet LLC | Specialties | 5615 C.L. Dees Rd | 826-5555 |
| Vancleave Chiropractic Clinic | Medical | 12004 Hwy 57 | 826-9977 |
| Vancleave Dry Cleaners | Dry Cleaning & Laundry Services | 12004 Hwy 57 | 826-5768 |
| Vancleave Family Medical Clinic * + | Medical | 12313 Hwy 57 | 826-1990 |
| Vancleave Glass | Construction, Services & Hardware | 12213 Hwy 57 | 826-1540 |
| Vancleave Lumber | Construction, Services & Hardware | 11704 Hwy 57 | 826-4211 |
| Vancleave Plumbing | Construction, Services & Hardware | 10701 Clearwater Rd | 826-1700 |
| Vancleave Real Estate + | Real Estate | 11932 Hwy 57 | 826-1999 |
| Wachovia Bank * | Financial | 12000 Hwy 57 | 826-5911 |
| West Stone LLC * | Construction, Services & Hardware | 10910 Hwy 57 | 217-0380 |
